| 6.5 | Class: T-box factors (T-box), Alignment |
| Aligned T-box sequences (Class 6.5): | |
LWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYV--NGEWVPGGKPEP-QAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQ---------------------IMLNSLHKYEPRIHIVRVGGP-----------QRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLD Brachyury LWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYV--NGEWVPAGKPE-VSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGGQ---------------------IMLNSLHKYEPQVHIVRVGSA-----------HRMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLD TBX19 LWLKFHRHQTEMIITKQGRRMFPFLSFNISGLDPTAHYNIFVDVILADPNHWRF--QGGKWVPCGKADTNVQGNRVYMHPDSPNTGAHWMRQEISFGKLKLTNNKGASNNNGQM-----------------VVLQSLHKYQPRLHVVEVNEDGTEDTSQP----GRVQTFTFPETQFIAVTAYQNTDITQLKIDHNPFAKGFRD TBR-1 LWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRF--QGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQM-----------------IVLQSLHKYQPRLHIVEVTEDGVEDLNEP----SKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRD TBR-2 LWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRY--QSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQM-----------------IVLQSLHKYQPRLHIVEVNDGEPEAACN----ASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRE TBX21 LWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADP-ATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGH--------------------IILNSMHRYQPRFHVVYVDPRKDSEKYA----EENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRD TBX1 LWEEFNQLGTEMIVTKAGRRMFPPFQVKILGMDSLADYALLMDFIPLDDKRYRYAFHSSAWLVAGKADP-ATPGRVHFHPDSPAKGAQWMRQIVSFDKLKLTNNLLDDNGH--------------------IILNSMHRYQPRFHVVFVDPRKDSERYA----QENFKSFIFTETQFTAVTAYQNHRITQLKIASNPFAKGFRE TBX10 LWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADS-PVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGH--------------------IILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRD TBX15 LWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADS-PVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNELDDQGH--------------------IILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRD TBX18 LWDKFHELGTEMIITKSGRRMFPTIRVSFSGVDPEAKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADP-PLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGH--------------------IILNSMHKYQPRVHIIKKKDHTASLLNLK---SEEFRTFIFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRD TBX20 LWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGH--------------------IILQSMHKYKPRVHVIEQGSSVDLSQIQSLP-TEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRD TBX22 LWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKF--HNSRWMVAGKADP-EMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGF--------------------TILNSMHKYQPRFHIVRANDILKLP-------YSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRD TBX2 LWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKF--HNSRWMVAGKADP-EMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLP-------YSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRD TBX3 LWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKF--CDNKWMVAGKAEP-AMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH--------------------IILNSMHKYQPRLHIVKADENNAFGSKN-----TAFCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFRG TBX4 LWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEP-AMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH--------------------IILNSMHKYQPRLHIVKADENNGFGSKN-----TAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRG TBX5 LWKEFSSVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVIPVDGARYRW--QGRRWEPSGKAEP-RLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGH--------------------LILHSMHKYQPRIHLVRAAQLCSQH-------WGGMASFRFPETTFISVTAYQNPQITQLKIAANPFAKGFRE TBX6 MWNEFYHRSTEMILTKQGRRMFPYCRYWITGLDSNLKYILVMDISPVDNHRYKW--NGRWWEPSGKAEP-HVLGRVFIHPESPSTGHYWMHQPVSFYKLKLTNNTLDQEGH--------------------IILHSMHRYLPRLHLVPAEKAVEVIQLN----GPGVHTFTFPQTEFFAVTAYQNIQITQLKIDYNPFAKGFRD MGA